Department of Biological Sciences
Indian Institute of Science Education and Research Bhopal


Personal Details


  • Name: Dr. Sanjeev Shukla
  • Designation: Assistant Professor
  • Department: Biological Sciences
  • E-Mail: sanjeevs[AT]iiserb.ac.in
  • Phone: +91 755 269 1409, 669 1409


Awards and Fellowships


  • April 2017-present: Wellcome Trust/ DBT India Alliance Intermediate Fellow

Academic Details


  • Assistant Professor (May 2013-): Biological Sciences, Indian Institute of Science, Education and Research (IISER) Bhopal
  • Postdoctoral Fellow (March 2010-March 2013): National Cancer Institute, National Institutes of Health, Maryland, USA
  • Postdoctoral Fellow (May 2009-Feb 2010): Georgetown University Medical Centre, Washington DC, USA
  • Ph.D. (Nov 2003-Feb 2009): Advanced Centre for Treatment, Research and Education in Cancer (CRI-ACTREC), Navi Mumbai

Interplay Between Epigenetic Changes And Alternative Pre-MRNA Splicing In Tumorigenesis


  • Examination of DNA methylation mediated regulation of alternative splicing via modulation of reciprocal binding of CTCF and BORIS in cancer cells.
  • Analysis of DNA binding proteins/ transcription factors and upstream pathways that are involved in regulation of alternative splicing
  • Examination of role of cancer specific alternative spliced isoforms in tumorigenesis
Authors Title of Article Journal Year
Sathiya Pandi Narayanan
Smriti Singh
Sanjeev Shukla
A saga of cancer epigenetics: linking epigenetics to alternative splicing Biochemical J 2017
Smriti Singh
Sathiya Pandi Narayanan
Kajal Biswas
Amit Gupta
Neha Ahuja
Sandhya Yadav
Rajendra Kumar Panday
Atul Samaiya
Shyam K Sharan
Sanjeev Shukla
Intragenic DNA methylation and BORIS-mediated cancer-specific splicing contribute to the Warburg effect Proceedings of the National Academy of Sciences 2017
Ryan J Marina
David Sturgill
Marc A Bailly
Morgan Thenoz
Garima Verma
Maria F Prigge
Kyster K Nanan
Sanjeev Shukla
Nazmul Haque
Shalini Oberdoerffer
TET-catalyzed oxidation of intragenic 5-methylcytosine regulates CTCF-dependent alternative splicing EMBO J 2016
Sathiya Pandi Narayanan
Smriti Singh
Amit Gupta
Sandhya Yadav
Shree Ram Singh
Sanjeev Shukla
Integrated genomic analyses identify KDM1A’s role in cell proliferation via modulating E2F signaling activity and associate with poor clinical outcome in oral cancer Cancer Letters 2015

Open Positions


  • I am looking for postdoctoral candidate who is interested to study epigenetic regulation of alternative pre-mRNA splicing/RNA processing in tumorigenesis. Interested candidate can send their cv and statement of research interest by email to me at sanjeevs@iiserb.ac.in

    Epigibility: Candidate should have PhD in biological sciences from recognized university/institution.

    Desirable: Prior experience with molecular biology techniques. Candidates with experience in analysis of next-generation sequencing data/ RNA work / chromatin biology are encouraged to apply.

PhD Students


  • Smriti Singh
    smritis@iiserb.ac.in
  • Amit Gupta
    gamit@iiserb.ac.in
  • Sandhya Yadav
    syadav@iiserb.ac.in
  • Neha Ahuja
    nehavs2@iiserb.ac.in