Department of Biological Sciences
Indian Institute of Science Education and Research Bhopal


Personal Details




Academic Details


  • Associate Professor October 2015
  • Assistant Professor (December 2009- August 2015), Biology, Indian Institute of Science Education and Research, Bhopal, India.
  • Post doctoral fellow (August 2007 – November 2009) Max Planck Institute of Molecular Cell Biology and genetics, Dresden, Germany with Prof. Marino Zerial.
  • Post doctoral fellow (January 2004 – July 2007) Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York, USA with Prof. Richard A. Cerione.
  • Ph.D. (August 1997 – September 2003) Molecular Biophysics Unit, Indian Institute of Science, Bangalore, India with Prof. M. Vijayan.
  • M.Sc. in Biophysics, Molecular Biology and Genetics. Raja Bazar Science College Calcutta University.

Position Available


  • Postdoctoral fellow: Cell biology of cancer metastasis. Exposure to fluorescence microscopy is preferred.
  • Junior research fellow: Biophysical and cellular studies on calcium binding protein from Entamoeba histolytica. Contact sunando@iiserb.ac.in

Research Interest


  • Vesicular trafficking and Cancer metastasis.
Authors Title of Article Journal Year
Kuldeep Verma
sunando datta
Heavy subunit of cell surface Gal/GalNAc lectin (Hgl) undergoes degradation via endo-lysosomal compartments in Entamoeba histolytica. Small GTPases 2017
Amulya Priya
Jini Sugatha
Sameena Parveen
sandra Lacas-Jarvais
Jerome Gilleron
Sunando Datta
Essential and selective role of SNX12 in transport of endocytic and retrograde cargo Journal of Cell Science 2017
Kuldeep Verma
The monomeric GTPase Rab35 regulates phagocytic cup formation and phagosomal maturation in Entamoeba histolytica Journal of Biological Chemistry 2017
Rupali Yadav
Vijay Sherivastava
Watanabe Natsuki
Priya Tomar
Madhumita Mukherjee
samudrala Gourinath
Kumiko Nakada-Tsukai
Tomoyoshi Nozaki
Sunando Datta
Structural and thermodynamic characterization of metal binding in Vps29 from Entamoeba histolytica: Implication in retromer function. Molecular Microbiology 2017
Rupali Yadav
Kuldeep Verma
MIntu Chandra
Madhumita Mukherjee
Sunando Datta
Biophysical studies on calcium and carbohydrate binding to carbohydrate recognition domain of Gal/GalNAc lectin from Entamoeba histolytica: insights into host cell adhesion. J. Biochemistry 2016
Vijay Srivastava
Mintu Chandra
Yumiko Saito-Nakano
Tomoyoshi Nozaki
Sunando Datta
Crystal Structure Analysis of Wild Type and Fast Hydrolyzing Mutant of EhRabX3, a Tandem Ras Superfamily GTPase from Entamoeba histolytica Journal of Molecular Biology 2016
Kuldeep Verma
Tomo Nozaki
Sunando Datta
Role of EhRab7A in phagocytosis of type 1 fimbriated E. coli by Entamoeba histolytica. Molecular Microbiology 2016
Mintu Chandra
Sunando Datta
Role of cysteine residues in the redox-regulated oligomerization and nucleotide binding to EhRabX3. Molecular and Biochemical Parasitology 2016
Mintu Chandra
Runjhun Saran
Sunando Datta
Deciphering the role of Atg5 in nucleotide dependent interaction of Rab33B with the dimeric complex, Atg5-Atg16L1. Chandra M, Saran R, Datta S. Biophysical and Biochemical Research Communication 2016
Merlyn Emmanuel
Yumiko Saito-Nakano
Tomoyoshi Nozaki
Sunando Datta
Small GTPase Rab21 mediates fibronectin induced actin reorganization in Entamoeba histolytica: implications in pathogen invasion. PLOS Pathogen 2015
Amulya Priya
Inna Kalaidzidis
Yannis Kalaidzidis
David Lambright
Sunando Datta
Molecular insights into Rab7-mediated endosomal recruitment of core retromer: deciphering the role of Vps26 and Vps35. Traffic 2015
Kuldeep Verma
Insights into endosomal maturation of human holo-transferrin in the enteric parasite Entamoeba histolytica: essential roles of Rab7A and Rab5 in biogenesis of giant early endocytic vacuoles. Cellular Microbiology 2015
Vijay Srivastava
Mintu Chandra
Sunando Datta
Crystallization and preliminary X-ray analysis of RabX3, a tandem GTPase from Entamoeba histolytica Acta Crystallographica section F 2014
Mintu Chandra
Madhumita Mukherjee
Vijay Srivastava
Yumiko Saito-Nakano
Tomoyoshi Nozaki
Sunando Datta
Insights into the GTP/GDP cycle of RabX3, a novel GTPase from Entamoeba histolytica with tandem G-domains. Biochemistry 2014
Vineet Sadarangani
Sunando Datta
Manonmani Arunachalam
New players in the same old game: a system level in silico study to predict type III secretion system and effector proteins in bacterial genomes reveals common themes in T3SS mediated pathogenesis. BMC Research Notes 2013

PhD Students


  • Priyanka Sharma: Understanding the role of vesicular trafficking in breast cancer metastasis
  • Rupali Yadav: Structural biology on amoebic virulence factors.
  • Aashutosh Tripati: VPS9 domain exchange factors from E. histolytica
  • Anil Narroka: DENN domain exchange factors from E. histolytica
  • Ebsy jaimon: Study of mechanical properties of breast cancer cells by microfluidics in collaboration with Dr. Ashish Kumar Sen, Dept. of Mechanical Engineering, IIT Madras
  • Sameena Parveen: Role of SNARES in cancer cell invasion.
  • Jini Sugatha: Proteomics of Snx12

Junior Research Fellow


  • Lekha Vinod Shah: Role of MT2MMP in breast cancer cell invasion

Post-Doctoral Fellow


  • Dr. Kuldeep Verma: Rab GTPases in Phagocytosis by E. histolytica
  • Dr. Vijay Kumar Srivastava: Structural biology on amoebic virulence factors